Benefits:
• PROMOTES THE ERECTILE FUNCTION OF THE PENIS WITH FIRMER AND HARDER ERECTIONS
• INTENSIFIES YOUR LIBIDO AND APPETITE FOR SEXUAL PLEASURE
• STRENGTHENS YOUR SEXUAL STAMINA
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How VigaPlus™ works?
VigaPlus™ works on the same principle as VIAGRA, CIALIS and LEVITRA
It works by increasing the Nitric Oxide level in the blood plasma,
which causes the smooth muscles to relax leading to vasodilation of the
penile arteries and thereby an erection.
Scientific explanation:
NO is produced from the amino acid L-arginine by the enzymatic action of nitric oxide synthase (NOS). There are two endothelial forms of NOS: constitutive NOS (cNOS; type III) and inducible NOS (iNOS;
type II). Under normal, basal conditions in blood vessels, NO are
continually being produced by cNOS. When NO forms, it has a half-life
of only a few seconds, in large part because superoxide anion has a
high affinity for NO (both molecules have an unpaired electron making
them highly reactive). Therefore, superoxide anion reduces NO
bioavailability. NO also avidly binds to the heme moiety of haemoglobin
(in red blood cells) and the heme moiety of the enzyme guanylyl cyclase,
which is found in vascular smooth muscle cells and most other cells of
the body. Therefore, when NO is formed by vascular endothelium, it
rapidly diffuses into the blood where it binds to haemoglobin and
subsequently broken down. It also diffuses into the vascular smooth
muscle cells adjacent to the endothelium where it binds to and
activates guanylyl cyclase. This enzyme catalyzes the dephosphorylation
of GTP to cGMP, which serves as a second messenger
for many important cellular functions, particularly for signalling
smooth muscle relaxation.

Cyclic GMP induces smooth muscle relaxation by multiple mechanisms including
1. increased intracellular cGMP, which inhibits calcium entry into the cell, and decreases intracellular calcium concentrations
2. activates K+ channels, which leads to hyperpolarization and relaxation
3.
Stimulates a cGMP-dependent protein kinase that activates myosin light
chain phosphatase, the enzyme that dephosphorylates myosin light
chains, which leads to smooth muscle relaxation.
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Because of the central role of cGMP in NO-mediated vasodilation, drugs
(e.g., Viagra® , VigaPlus™) that inhibit the breakdown of cGMP
(cGMP-dependent phosphodiesterase inhibitors) are used to enhance
NO-mediated vasodilation, particularly in penile erectile tissue in the
treatment of erectile dysfunction
To help you understand this even better, please take help of the
following diagrams that will help us to explain you better.


The
penis has two paired cylinders called the Corpora Cavernosum that, when
aroused, expand and fill with blood creating the hardness of your
erection
In impotent men the erectile
capacity of the Corpora Cavernosum diminishes or goes to zero because
of a variety of reasons such as vasoconstriction of the arteries
supplying blood to it, inhibition of cGMP causing the smooth muscles
around the arteries to be in a state of constant contraction or
systemic failure of the hypothalamus or the pleasure centre in the
brain to release parasympathetic signals. VigaPlus™ reverses the above
through the use of its key ingredients L-Arginine and Maca by
activating the production of NO in the blood plasma and restricting any
cGMP inhibition, causing vasodilation of the penile arteries and muscle
relaxation of the smooth muscles causing easy blood flow in the Corpora
Cavernosum, which once filled with blood causes an instant erection.
“NO
OTHER PRODUCT, INCLUDING PHARMACEUTICAL ALTERNATIVES CAN MATCH THE
EFFECIENCY IMN GIVING AN INSTANT ERECTION AND LONG TERM BENEFITS THAN
VigaPlus™ PROVIDES ”
What results can I expect?
VigaPlus™ gives instant erections, working in 30 minutes flat.
Compared to the other pharmaceutical alternatives VigaPlus™ has the following advantages:
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1. Works in 15-30mins after ingestion
2. Lasts 4 to 6 hours!
3. Zero side effects
4. Long term permanent cure
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See
the following comparative graphs to know for yourself, how VigaPlus™
beats the competition hollow when it comes to providing the ultimate
solution to your erection problems
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